@article {385,
	title = {Baseline expression of heat-shock proteins (HSPs) of a "thermotolerant" Mediterranean marine species largely influenced by natural temperature fluctuations},
	journal = {Can.J.Fish.Aquat.Sci.},
	volume = {63},
	year = {2006},
	abstract = {<p>Northwestern Mediterranean warming-related disease outbreaks and species  shifts have recently been documented. Biomarkers of short-term effects  on the health or resistance of organisms are necessary to assess and  understand mechanisms affecting marine biodiversity. Heat-shock protein  (HSP) expression was here believed to present finer variations than  previously reported in experimental studies, which we tested to assess  HSP sensitivity and relevance in the global warming context. One  population of the \&quot;thermophilic\&quot; marine cave mysid Hemimysis margalefi  was monitored over 4 years. Three HSPs presented recurrent expression.  Among them, HSP50 and HSP60 expressions varied seasonally with  environmental temperature. HSP60 expression displayed the greatest  variability and was most closely related to temperature fluctuations.  Multiple regression showed that while the main stressor was temperature,  demographic variables (proportion of immatures, proportion of gravid  females) also influenced expression variability. Such a monitoring of  HSP baseline expression in a natural population had only rarely been  conducted. HSPs are, however, good biomarkers to evaluate the effects of  warming episodes or heat stress in the wild. This study provides  essential spatial and temporal reference for further experimental and in  situ analyses and is a prerequisite to diagnostic and predictive  approaches.</p>},
	keywords = {biodiversit{\'e}, biodiversity, climate change, disease, global warming, grotte sous-marine, health, heat-shock protein, Hemimysis sp., marine cave, Mer M{\'e}diterran{\'e}e, monitoring, physiologie, protein, prot{\'e}ine de choc thermique, r{\'e}chauffement, r{\'e}chauffement global, sea water temperature, temperature, temp{\'e}rature de l{\textquoteright}eau de mer, thermotolerance, warming},
	author = {C. Lejeusne and T. Perez and V. Sarrazin and P. Chevaldonn{\'e}}
}
