@proceedings {477,
	title = {Sponge chemical defences in stress conditions: the case study of the last disease outbreak observed in N-W Mediterranean},
	year = {2008},
	address = {Marseille},
	abstract = {<p>An increase in frequency of epizootic events and mass mortalities have  been related with the warming trend of the NW Mediterranean. The present  study focuses on Spongia officinalis, a commercial sponge species  particularly threatened by the sea warming. The aim of this work was to  acquire fundamental data about the biology of this sponge and the  mechanisms of health alteration. The stress level of sponges was  revealed by measuring Heat Shock Proteins (HSP) expression, a protein  family involved in maintaining homeostasis. In parallel, we studied the  expression of indicators of the sponge chemical defences. These  indicators result from the secondary metabolism and are measured by  assessing the sponge natural toxicity and then searching the expression  level of certain secondary metabolites</p>},
	keywords = {biology, climate change, disease, Europe, health, heat-shock protein, mass mortality, Mediterranean sea, mortality, north-western Mediterranean, protein, research, secondary metabolite, sponge, Spongia officinalis, trend, warming},
	author = {V. Sarrazin and T. Perez}
}
